Calcium carbonate nanoparticles stimulate tumor metabolic reprogramming and modulate tumor metastasis
نویسندگان
چکیده
منابع مشابه
Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo.
The acidic extracellular environment of tumors potentiates their aggressiveness and metastasis, but few methods exist to selectively modulate the extracellular pH (pHe) environment of tumors. Transient flushing of biological systems with alkaline fluids or proton pump inhibitors is impractical and nonselective. Here we report a nanoparticles-based strategy to intentionally modulate the pHe in t...
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ژورنال
عنوان ژورنال: Nanomedicine
سال: 2019
ISSN: 1743-5889,1748-6963
DOI: 10.2217/nnm-2018-0302